High Purity API Veliparib Dihydrochloride Powder CAS 912445-05-7 Anti-Tumor Treatment Abt-888

Basic Info

Model NO.	912445-05-7
Colour	White
Boiling Point	656.2±70.0 °c
Melting Point	381.5±35.7 °c
Molecular Weight	317.2
Density	1.5±0.1 g/cm3
Transport Package	as Request
Specification	99%
Trademark	Kunsui
Origin	China
HS Code	2932999099
Production Capacity	60000

Product Description

Veliparib hydrochloride (ABT-888) is an orally active PARP1/2 inhibitor. It first entered the clinic in 2007. So far, a total of 90 clinical studies have been carried out. The indications include: triple-negative breast cancer, non-small cell Chemicalbook lung cancer, ovarian cancer, melanoma, brain cancer, etc. ABT-888 is used in combination with DNA-damaging chemotherapeutic drugs for the treatment of glioblastoma multiforme, epithelial ovarian cancer, and metastatic brain cancer.The biggest difference between ABT-888 and other PARP inhibitors is that the combination of ABT-888 and chemotherapy drugs to treat tumors is carried out in patients without genotyping, while ABT-888, BMN-673, Rui Chemicalbook Kapabu, etc. is the first to target patients with BRCA-mutated tumors. In addition to chemotherapy, there is currently no good targeted therapy for triple-negative breast cancer. If ABT-888 can be successful, it will well meet this clinical gap.

Packing and storage:
In 25kg, 50kg, 1000kg net bags, store at a cool, dry and well ventilated place.

Product Name	Veliparib dihydrochloride
CAS	912445-05-7
Purity	99%

Items	Standards		Results
Appearance	White or off-white crystalline powder		Complies
Identification	By IR		Complies
	By HPLC		Complies
Solubility	slightly soluble in water		Complies
Water Content	3.00%~4.40%		3.60%
Melting Point	69~75ºC		73.4~74.7ºC
Heavy Metal	≤20ppm		Complies
Isomer	≤0.15%		0.03%
	13.6%~16.6%		15.3%
Purity(HPLC)	≥99.50%		99.88%
Assay (HPLC basis on drying)	98.0%~102.0%		99.96%
Particle Size	D90: ≤50µm, D98: ≤80µm		30µm, 38µm

Packing and Storage: Packed in double plastic bags inside, outside with 25kg Fiber Drum.
Drum Size: 40cm*40cm*50mm, 25KG/drum Nt.;27.5Kg/drum.Gt. Store in a well-closed container away from moisture.
Shelf Life: 2 years if sealed and store away from direct sun light.
Storage: Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat.
Delivery time: Around 3-5 workdays after your payment.
Q1: How to confirm the Product Quality before placing orders?
A: By sending you our available samples. Or if you have special requirement on the goods, we can prepare samples according to your requirement and send to you for your confirmation.
Q2: Can you supply free samples?
A: Yes, we can provide some free sample, but the shipping cost should be on the customers' account. You can either pay us the shipping cost or arrange a courier to collect the samples.
Q3: What's the MOQ?
A: The minimum order quantity for most of our products is 1kg.
Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price.
Q5: How to place order and make payment?
A: You can send our your Purchase order(if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation., then you can make payment accordingly.
Q6: How do you treat quality complaint?
A: All our products are strictly tested by our QC, and confirmed by QA; unqualified material will not be released to customer. In case any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.