High Purity API Veliparib Dihydrochloride Powder CAS 912445-05-7 Anti-Tumor Treatment Abt-888
Basic Info
Model NO. | 912445-05-7 |
Colour | White |
Boiling Point | 656.2±70.0 °c |
Melting Point | 381.5±35.7 °c |
Molecular Weight | 317.2 |
Density | 1.5±0.1 g/cm3 |
Transport Package | as Request |
Specification | 99% |
Trademark | Kunsui |
Origin | China |
HS Code | 2932999099 |
Production Capacity | 60000 |
Product Description
Veliparib hydrochloride (ABT-888) is an orally active PARP1/2 inhibitor. It first entered the clinic in 2007. So far, a total of 90 clinical studies have been carried out. The indications include: triple-negative breast cancer, non-small cell Chemicalbook lung cancer, ovarian cancer, melanoma, brain cancer, etc. ABT-888 is used in combination with DNA-damaging chemotherapeutic drugs for the treatment of glioblastoma multiforme, epithelial ovarian cancer, and metastatic brain cancer.The biggest difference between ABT-888 and other PARP inhibitors is that the combination of ABT-888 and chemotherapy drugs to treat tumors is carried out in patients without genotyping, while ABT-888, BMN-673, Rui Chemicalbook Kapabu, etc. is the first to target patients with BRCA-mutated tumors. In addition to chemotherapy, there is currently no good targeted therapy for triple-negative breast cancer. If ABT-888 can be successful, it will well meet this clinical gap.
Packing and storage:
In 25kg, 50kg, 1000kg net bags, store at a cool, dry and well ventilated place.
Product Name | Veliparib dihydrochloride |
CAS | 912445-05-7 |
Purity | 99% |
Items | Standards | Results | |
Appearance | White or off-white crystalline powder | Complies | |
Identification | By IR | Complies | |
By HPLC | Complies | ||
Solubility | slightly soluble in water | Complies | |
Water Content | 3.00%~4.40% | 3.60% | |
Melting Point | 69~75ºC | 73.4~74.7ºC | |
Heavy Metal | ≤20ppm | Complies | |
Isomer | ≤0.15% | 0.03% | |
13.6%~16.6% | 15.3% | ||
Purity(HPLC) | ≥99.50% | 99.88% | |
Assay (HPLC basis on drying) | 98.0%~102.0% | 99.96% | |
Particle Size | D90: ≤50µm, D98: ≤80µm | 30µm, 38µm |
Packing and Storage: Packed in double plastic bags inside, outside with 25kg Fiber Drum.
Drum Size: 40cm*40cm*50mm, 25KG/drum Nt.;27.5Kg/drum.Gt. Store in a well-closed container away from moisture.
Shelf Life: 2 years if sealed and store away from direct sun light.
Storage: Stored in a clean, cool, dry area; keep away from moisture and strong, direct light/heat.
Delivery time: Around 3-5 workdays after your payment.
Q1: How to confirm the Product Quality before placing orders?
A: By sending you our available samples. Or if you have special requirement on the goods, we can prepare samples according to your requirement and send to you for your confirmation.
Q2: Can you supply free samples?
A: Yes, we can provide some free sample, but the shipping cost should be on the customers' account. You can either pay us the shipping cost or arrange a courier to collect the samples.
Q3: What's the MOQ?
A: The minimum order quantity for most of our products is 1kg.
Q4: Is there any discount?
A: Yes, for larger quantity, we always support with better price.
Q5: How to place order and make payment?
A: You can send our your Purchase order(if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation., then you can make payment accordingly.
Q6: How do you treat quality complaint?
A: All our products are strictly tested by our QC, and confirmed by QA; unqualified material will not be released to customer. In case any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.